BDBM50395275 CHEMBL2163616

SMILES COCCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1

InChI Key InChIKey=JPEZXBCEWYKFBS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395275   

TargetMAP kinase-activated protein kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395275(CHEMBL2163616)
Affinity DataIC50: 130nMAssay Description:Inhibition of MAPKAP-K2 using KKLNRTLSVA as substrate and [33P]-gamma-ATP after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395275(CHEMBL2163616)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human MAPKAP-K2 in THP1 cells assessed as inhibition of LPS-induced TNFalpha production incubated 1 hr prior to LPS challenge measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395275(CHEMBL2163616)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of CDK2 after 60 mins using [33P]-gamma-ATP by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed