BDBM50395749 CHEMBL2164826

SMILES CN1CCN(CC(=O)N[C@@]2(C(=O)Nc3cc(Cl)c(Cl)cc23)c2ccc(Cl)cc2)CC1

InChI Key InChIKey=FOCFHCJIDLTWDC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395749   

TargetGrowth hormone secretagogue receptor type 1(Human)
Sanofi Research

Curated by ChEMBL
LigandPNGBDBM50395749(CHEMBL2164826)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Sanofi Research

Curated by ChEMBL
LigandPNGBDBM50395749(CHEMBL2164826)
Affinity DataKi:  249nMAssay Description:Displacement of [125I]-ghrelin from human GHSR1 expressed in CHO-CREluc cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Sanofi Research

Curated by ChEMBL
LigandPNGBDBM50395749(CHEMBL2164826)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human GHSR1 expressed in CHO-CREluc cells after 4 hrs by Luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed