BDBM50395938 CHEMBL2164549

SMILES Fc1cc(cc(c1)-c1nc(no1)-c1cnccn1)C#N

InChI Key InChIKey=NBLCXLMMHPGZSD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395938   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395938(CHEMBL2164549)
Affinity DataIC50:  4.70E+3nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed