BDBM50395941 CHEMBL2164546

SMILES Fc1cc(cc(c1)-c1noc(n1)-c1ccccn1)C#N

InChI Key InChIKey=WZPADMVXGDUSLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395941   

TargetMetabotropic glutamate receptor 5(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395941(CHEMBL2164546)
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed