BDBM50395942 CHEMBL2164545

SMILES Fc1cc(cc(c1)-c1nc(co1)-c1ccccn1)C#N

InChI Key InChIKey=PURMTHHDJDASBS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50395942   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395942(CHEMBL2164545)
Affinity DataIC50:  22nMAssay Description:Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells expressing GLAST assessed as inhibition of DHPG-induced intracel...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed