BDBM50396233 CHEMBL2172182::US8569318, 1.1(3)

SMILES CN1CCc2c(C1)cnc1c(c(C)nn21)S(=O)(=O)c1ccccc1

InChI Key InChIKey=HXWBAPBYAWNJPM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396233   

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50396233(CHEMBL2172182 | US8569318, 1.1(3))
Affinity DataKi:  60nM IC50: 13nMAssay Description:Activity test of serotonin 5-HT6 receptor antagonists of the general formulas 1, 2 in the setting of competitive binding to serotonin 5-HT6 receptors...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2014
Entry Details
US Patent

Target5-hydroxytryptamine receptor 6(Human)
TBA

US Patent
LigandPNGBDBM50396233(CHEMBL2172182 | US8569318, 1.1(3))
Affinity DataKi:  60.4nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptor expressed in HeLa cells after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed