BDBM50396263 CHEMBL2172315
SMILES CC(C)NC(=O)[C@H]1CC[C@H](CC1)n1c(NC(=O)c2cc(F)cc(F)c2)nc2ccc(CN3CCC(CC3)C(C)(C)O)cc12
InChI Key InChIKey=GZYCQQBRSRIFII-JAQLMMITSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50396263
Affinity DataKd: 0.240nMAssay Description:Binding affinity to human ALK by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 72nMAssay Description:Binding affinity to human MER by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 25nMAssay Description:Binding affinity to human MAP4K2 by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 8.20nMAssay Description:Binding affinity to human LTK by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 110nMAssay Description:Binding affinity to human LCK by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataKd: 72nMAssay Description:Binding affinity to human INSR by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMAssay Description:Binding affinity to human AXL by Ambit titration assayMore data for this Ligand-Target Pair
Affinity DataIC50: 536nMAssay Description:Inhibition of INSR expressed in CHO cells assessed as inhibition of receptor phosphorylation pre-incubated before insulin stimulation by Meso-Scale D...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK enzymeMore data for this Ligand-Target Pair
Affinity DataKd: 5.60nMAssay Description:Binding affinity to human IRAK1 by Ambit titration assayMore data for this Ligand-Target Pair