BDBM50396459 CHEMBL2170640
SMILES NC(=N)NC(=O)c1ccc(N2CCC(CC2)NC(=O)c2ccc[nH]2)c(c1)C(F)(F)F
InChI Key InChIKey=RGQILMPUTAKOOX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50396459
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Inhibition of NHE1 in human platelet rich plasma assessed as reduction of propionate medium induced platelet swelling measured every 6 secs for 5 min...More data for this Ligand-Target Pair
TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Boehringer Ingelheim Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 41nMAssay Description:Inhibition of NHE1 in human HT-29 cells assessed as intracellular pH change after 30 minsMore data for this Ligand-Target Pair