BDBM50397666 CHEMBL2017277

SMILES COc1cc2c(NC3CCCCC3)c(cnc2cc1-c1c(C)noc1C)C(N)=O

InChI Key InChIKey=MWCQWHMNJUFCOD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50397666   

TargetBromodomain-containing protein 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50397666(CHEMBL2017277)
Affinity DataIC50: 501nMAssay Description:Binding affinity to BRD3 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50397666(CHEMBL2017277)
Affinity DataIC50: 1.26E+3nMAssay Description:Binding affinity to BRD4 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50397666(CHEMBL2017277)
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to human BRD2 assessed as inhibition of Alexa Fluor 488 binding after 60 mins by fluorescence anisotropic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50397666(CHEMBL2017277)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50397666(CHEMBL2017277)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of CYP3A4 using diethoxyfluoresin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed