BDBM50397892 CHEMBL2179527
SMILES Fc1coc(c1)C(=O)N1CC2CNCC2C1
InChI Key InChIKey=PLQXXAVXCSTSDP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50397892
Affinity DataKi: 21nM ΔG°: -10.3kcal/moleT: 21°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in human SH-EP1 cells after 2 hrs by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 36nM ΔG°: -10.0kcal/moleT: 21°CAssay Description:The binding of [3H]MLA was measured using a modification of the methods of Davies et al., Neuropharmacol. 38: 679 (1999). [3H]MLA (Specific Activity=...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at alpha4beta2 nAChR in human SH-EP1 cells assessed as calcium flux by calcium4-based FLIPR assayMore data for this Ligand-Target Pair