BDBM50398004 CHEMBL2180401

SMILES COc1cccc2C(=O)N(CCc3nc4ccccc4c(=O)n3-c3ccc4cnn(C)c4c3)C(=O)c12

InChI Key InChIKey=NEESGQXVXUXADB-UHFFFAOYSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398004   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50398004(CHEMBL2180401)Copy SMILESCopy InChI

Affinity DataKi:  0.950nMAssay Description:Inhibition of PDE10A by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50398004(CHEMBL2180401)Copy SMILESCopy InChI

Affinity DataKi:  0.950nMAssay Description:The activity of the compounds in accordance with the present invention as PDE10 inhibitors may be readily determined without undue experimentation us...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
3/9/2015
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL