BDBM50398064 CHEMBL2181927
SMILES CCOc1ncc(C)c2N=C(C)C([C@@H](c3ccc(cc3OC)C#N)c12)C(N)=O
InChI Key InChIKey=SWMKDVDOUGHTGK-ZYMOGRSISA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50398064
Affinity DataIC50: 16nMAssay Description:Antagonist activity against human mineralocorticoid receptor expressed in CHOK1 cells after 10 to 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Compound was evaluated for the inhibition of rat brain KYN 3-OHaseMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at Gal4-fused human MR LBD (734 to 985 residues) expressed in CHO-K1 cells after 5 to 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Antagonist activity at mineralocorticoid receptor (unknown origin)More data for this Ligand-Target Pair