BDBM50398257 CHEMBL2177872

SMILES Cc1ncc(CO)c2c(Nc3cnccn3)c(NCc3ccccc3)oc12

InChI Key InChIKey=MRFOZMCXMJFMOS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50398257   

TargetToll-like receptor 8(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50398257(CHEMBL2177872)
Affinity DataEC50:  9.79E+3nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells assessed as induction of NF-kappaB activity by measuring extracellular secreted alkaline pho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed