BDBM50398456 CHEMBL2179119

SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc2[nH]c(cc12)-c1ccccc1

InChI Key InChIKey=HFDJAPMETZJFMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398456   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50398456(CHEMBL2179119)
Affinity DataIC50:  3nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50398456(CHEMBL2179119)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM50398456(CHEMBL2179119)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human GST-tagged wild type EGFR ( 668 to 1210 residues) cytoplasmic domain expressed in baculovirus expression system prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed