BDBM50398661 CHEMBL2178141::US8796296, 24

SMILES CCNc1nc(Nc2cc3CN(CC(C)(C)O)C(=O)c3cc2OC)ncc1C(F)(F)F

InChI Key InChIKey=ZHMRQZAPJXOLBW-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398661   

LigandPNGBDBM50398661(CHEMBL2178141 | US8796296, 24)
Affinity DataKi:  3nMAssay Description:his assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. In 38...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

LigandPNGBDBM50398661(CHEMBL2178141 | US8796296, 24)
Affinity DataKi:  4nMAssay Description:Inhibition of LRRK2 using FAM-LRRKtide as substrate after 120 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50398661(CHEMBL2178141 | US8796296, 24)
Affinity DataIC50: 22nMAssay Description:Inhibition of autophosphorylation of LRRK2 in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed