BDBM50398702 CHEMBL2178731

SMILES NC(=O)[C@H]1CC(=O)NCCC(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)N1

InChI Key InChIKey=MHHORFPFSAYJRI-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398702   

TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataIC50: 37nMAssay Description:Agonist activity at human MOR expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 15 mins by cAMP EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398702(CHEMBL2178731)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]U69,593 from human KOR expressed in HEK293 cells after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed