BDBM50398930 CHEMBL2178782

SMILES COc1ccc2CN(CCCCNC34CC5CC(C)(CC(C)(C5)C3)C4)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24

InChI Key

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50398930   

TargetAcetylcholinesterase(Rat)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 696nMAssay Description:Inhibition of AChE in Wistar rat brain homogenates using acetylthiocholine iodide and DTNB as substrate after 10 mins by Ellman methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum - University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Alma Mater Studiorum - University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2B expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Human)
Alma Mater Studiorum - University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine as substrate preincubated for 20 mins followed by substrate addition measured for 3 mins by E...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Alma Mater Studiorum - University of Bologna

Curated by ChEMBL
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataIC50: 5.74E+3nMAssay Description:Inhibition of NMDA/glycine-activated rat GluN1/Glu2A expressed in xenopus laevis oocytes at -75 mV holding potential by voltage clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50398930(CHEMBL2178782)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]Ifenprodil from NMDAR-2B in Sprague-Dawley rat frontal cortex homogenates after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed