BDBM50399282 CHEMBL2180817::US9102622, 13.4

SMILES FS(=O)(=O)CCCCCc1ccc(OCc2ccccc2)cc1

InChI Key InChIKey=XWMLTTOAYSGFCX-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50399282   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Connecticut

US Patent
LigandPNGBDBM50399282(CHEMBL2180817 | US9102622, 13.4)
Affinity DataKi:  15nM ΔG°:  -11.1kcal/mole IC50: 180nMT: 2°CAssay Description:All compound solutions are made to a concentration of 10 mM in DMSO. To test the stability of the compounds in enzyme assay conditions, 25 nmoles of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2016
Entry Details
US Patent

TargetCannabinoid receptor 1(Rat)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50399282(CHEMBL2180817 | US9102622, 13.4)
Affinity DataKi:  118nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Mouse)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50399282(CHEMBL2180817 | US9102622, 13.4)
Affinity DataKi:  194nMAssay Description:Displacement of [3H]CP-55,940 from mouse CB2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50399282(CHEMBL2180817 | US9102622, 13.4)
Affinity DataIC50: 201nMAssay Description:Inhibition of recombinant human hexahistidine-tagged MGL expressed in Escherichia coli using AHMMCE as substrate after 15 mins by medium throughput f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed