BDBM50399333 CHEMBL2177142::US9364459, D

SMILES COc1cc(cc(OC)c1OC)C1=C(C(=O)NC1=O)c1c[nH]c2ccncc12

InChI Key InChIKey=JJIWTVPITVCQSQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50399333   

TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50: 23nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg University of Mainz

Curated by ChEMBL
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50: 40nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Johannes Gutenberg University of Mainz

Curated by ChEMBL
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50: 50nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50: 590nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Johannes Gutenberg-UniversitäT Mainz

US Patent
LigandPNGBDBM50399333(CHEMBL2177142 | US9364459, D)
Affinity DataIC50: 6.27E+3nMAssay Description:The effect of test compounds on the activity of the protein kinases GSK-3β, VEGFR-2 and FLT-3 was evaluated based on half maximal inhibitory con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent