BDBM50399370 CHEMBL2178274

SMILES Cc1ncn(-c2cc(NC(=O)c3ccc(C)c(-n4cc(-c5cnc6[nH]ncc6c5)nn4)c3)cc(C(F)(F)F)c2)n1

InChI Key InChIKey=UOVRWDKWWSPLGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50399370   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50399370BDBM50399370(CHEMBL2178274)
Affinity DataIC50: 1.94nMAssay Description:Inhibition of wild type Bcr-Abl using Tyr2 peptide as substrate after 2 hrs by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed