BDBM50399535 CHEMBL2180602

SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c2c1CCC\C2=C1\C(=O)Nc2ccc(F)cc12

InChI Key InChIKey=KGSRYTUWXUESJK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50399535   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Nanjing University of Technology

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of RET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Technology

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FLT-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Nanjing University of Technology

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)
Affinity DataIC50: 5nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Nanjing University of Technology

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)
Affinity DataIC50: 5nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)
Affinity DataIC50: 5nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)
Affinity DataIC50: 5nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Nanjing University of Technology

Curated by ChEMBL
LigandPNGBDBM50399535(CHEMBL2180602)
Affinity DataIC50: 10nMAssay Description:Inhibition of PDGFR-beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed