BDBM50399828 CHEMBL2180268

SMILES CCCC1CC(=O)C2C(C(C(=O)OC)=C(C)N=C2C1)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=DRYQKAWCIABIBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399828   

TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399828(CHEMBL2180268)
Affinity DataIC50: 400nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399828(CHEMBL2180268)
Affinity DataIC50: 400nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399828(CHEMBL2180268)
Affinity DataIC50: 4.05E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed