BDBM50399829 CHEMBL2180273

SMILES CCOC(=O)C1=C(C)N=C2CC(C)(C)CC(=O)C2C1c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=NPCZTDPKZMXZAZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399829   

TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399829(CHEMBL2180273)
Affinity DataIC50: 460nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399829(CHEMBL2180273)
Affinity DataIC50: 460nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTGF-beta receptor type-2(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50399829(CHEMBL2180273)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of TGBR2 signaling in human HEK293T cells assessed as inhibition of SMAD activation after 2 to 22 hrs by dual Luciferase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed