BDBM50400251 CHEMBL2179914

SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1Cc2ccc(nc2Nc2ccccc12)C(F)(F)F

InChI Key InChIKey=PDFNEHIIEMPNSC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400251   

TargetBombesin receptor subtype-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50400251(CHEMBL2179914)
Affinity DataIC50: 5.5nMAssay Description:Displacement of [125I]-[D-Tyr6,beta-Ala11,Phe13,Nle14]-Bombesin(6-14) from human BRS3 expressed in CHO cells expressing NFAT after 2 hrs by liquid sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50400251(CHEMBL2179914)
Affinity DataEC50:  110nMAssay Description:Agonist activity at human BRS3 expressed in HEK293 cells expressing aequorin measured for 30 secs by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBombesin receptor subtype-3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50400251(CHEMBL2179914)
Affinity DataEC50:  161nMAssay Description:Agonist activity at mouse BRS3 expressed in HEK293 cells expressing aequorin measured for 30 secs by bioluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed