BDBM50400306 CHEMBL2181086

SMILES CCN(CC)CCC(=O)Nc1cc2COCC=CCOCc3cccc(c3)-c3ccnc(Nc(c2)c1)n3

InChI Key InChIKey=ADOICFZLVOHSAF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50400306   

LigandPNGBDBM50400306(CHEMBL2181086)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400306(CHEMBL2181086)
Affinity DataIC50: 44nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400306(CHEMBL2181086)
Affinity DataIC50: 78nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400306(CHEMBL2181086)
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant JAK3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400306(CHEMBL2181086)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant JAK1 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed