BDBM50401170 CHEMBL2205793

SMILES CN1CCC(C)(C)c2cc3c(-c4ccc(s4)C(=S)N4CCCCC4)c4ccc(cc4sc3cc12)=[N+](C)C

InChI Key InChIKey=CRDBSWOEWIJYGP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50401170   

TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401170(CHEMBL2205793)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human His10-tagged P-gp ATPase activity expressed in BHK cells assessed as verapamil-induced inorganic phosphate release incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401170(CHEMBL2205793)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as inhibition of [3H]vinblastine efflux incubated for 30 mins prior to [3H]vinblastine additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetATP-dependent translocase ABCB1(Human)
The State University of New York

Curated by ChEMBL
LigandPNGBDBM50401170(CHEMBL2205793)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of MDR1 transfected in MDCK2 cells assessed as increase in calcein AM uptake incubated for 30 mins prior to calcein AM influx measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed