BDBM50402198 CHEMBL2203960

SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NC1(CCCCC1)C(=O)NCC#N

InChI Key InChIKey=HAWLJMVIYCHADS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50402198   

TargetCathepsin K(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50402198(CHEMBL2203960)
Affinity DataKi:  880nMAssay Description:Inhibition of human recombinant cathepsin K using Z-Leu-Arg-AMC as substrate after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin S(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50402198(CHEMBL2203960)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of human recombinant cathepsin S using Z-Phe-Arg-pNA as substrate after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50402198(CHEMBL2203960)
Affinity DataKi: >4.00E+4nMAssay Description:Inhibition of human recombinant cathepsin B using Z-Arg-Arg-pNA as substrate after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed