BDBM50405537 CHEMBL5269640

SMILES CCn1c(Cn2cc(nn2)-c2ccccc2)nn(CN2CCN(Cn3nc(Cn4cc(nn4)-c4ccccc4)n(CC)c3=S)CC2)c1=S

InChI Key InChIKey=ITLNEOSGHAJOIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405537   

Target72 kDa type IV collagenase(Human)
Adamas University

Curated by ChEMBL
LigandPNGBDBM50405537(CHEMBL5269640)
Affinity DataIC50: 376nMAssay Description:Inhibition of human recombinant MMP2 using chromogenic substrate (Ac-PLG-[2-mercapto-4-methyl-pentanoyl]-LG-OC2H5) incubated for 60 mins by colorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Adamas University

Curated by ChEMBL
LigandPNGBDBM50405537(CHEMBL5269640)
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant MMP-2 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50405537(CHEMBL5269640)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant MMP-9 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed