BDBM50405547 CHEMBL5291044

SMILES S=c1n(CN2CCN(Cn3nc(Cn4cc(nn4)-c4ccccc4)n(-c4ccccc4)c3=S)CC2)nc(Cn2cc(nn2)-c2ccccc2)n1-c1ccccc1

InChI Key InChIKey=JNJGJADWNMBMAR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405547   

TargetMatrix metalloproteinase-9(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandPNGBDBM50405547(CHEMBL5291044)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant MMP-9 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Adamas University

Curated by ChEMBL
LigandPNGBDBM50405547(CHEMBL5291044)
Affinity DataIC50: 468nMAssay Description:Inhibition of human recombinant MMP2 using chromogenic substrate (Ac-PLG-[2-mercapto-4-methyl-pentanoyl]-LG-OC2H5) incubated for 60 mins by colorimet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Adamas University

Curated by ChEMBL
LigandPNGBDBM50405547(CHEMBL5291044)
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant MMP-2 using Ac-PLG-[2-mercapto-4-methyl pentanoyl]-LG-OC2H5 as chromogenic substrate incubated for 60 mins by colorim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed