BDBM50405611 CHEMBL5273419

SMILES Fc1ccc2occ(\C=C\c3nc4cc(Cl)ccc4n3-c3ccccc3)c(=O)c2c1

InChI Key InChIKey=LXYDDJNLJOZZOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405611   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50405611(CHEMBL5273419)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50405611(CHEMBL5273419)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Aligarh Muslim University

Curated by ChEMBL
LigandPNGBDBM50405611(CHEMBL5273419)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of his-tagged recombinant human PDE10A catalytic domain extracted from Escherichia coli BL21(DE3) using [3H]-cAMP as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed