BDBM50405897 CHEMBL5277241

SMILES CC(=O)OCc1ccc2sc(cc2c1)S(N)(=O)=O

InChI Key InChIKey=JPSSAXLGXLTVNR-UHFFFAOYSA-N

Data  2 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50405897   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataKi: <1nMAssay Description:Vasopressin V2 receptor antagonistic activity in vivo in anesthetized ratsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataKi:  23nMAssay Description:Antagonistic activity against Thromboxane A2 receptor in guinea pig trachea in the presence of 11,9-epoxymethano-PGH2More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataIC50:  409nMAssay Description:Inhibitory activity against Neisseria gonorrhoeae dihydrofolate reductase at 10e8 MMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity against Neisseria gonorrhoeae dihydrofolate reductase at 10e8 MMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataIC50:  268nMAssay Description:Inhibitory activity against Neisseria gonorrhoeae dihydrofolate reductase at 10e8 MMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataIC50:  6.90nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase Lck(Human)
Incyte Research Institute

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)
Affinity DataIC50:  198nMAssay Description:The compound was tested for alpha-adrenergic activity against Alpha-1 adrenergic receptor from rat aorta.More data for this Ligand-Target Pair
In DepthDetails PubMed