BDBM50406376 CHEMBL5289332

SMILES CC1(N)CCN(CC1)c1nc2ncc(Sc3cccc(Cl)c3Cl)nc2[nH]1

InChI Key InChIKey=WXBBRUZOILNLED-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50406376   

LigandPNGBDBM50406376(CHEMBL5289332)
Affinity DataIC50: 47nMAssay Description:Allosteric inhibition of IRS1 peptide-activated human recombinant SHP2 (Met1 to Leu525) expressed in Escherichia coli assessed as inhibition of depho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed