BDBM50407356 CHEMBL54265

SMILES CN(C)CCc1c[nH]c2ccc(cc12)-n1cncn1

InChI Key InChIKey=GKKAQRFMUGUZQS-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50407356   

Target5-hydroxytryptamine receptor 1D(Pig)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 19.9nMAssay Description:Binding activity against 5-hydroxytryptamine 3 receptor from rat cortex homogenate using [3H]-Q-ICS 205-930 as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Pig)
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 20nMAssay Description:Compound was tested for its ability to displace [3H]-5-HT binding to 5-hydroxytryptamine 1D receptor recognition sites in pig caudate membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 25nMAssay Description:Compound was tested for its ability to displace [3H]8-OH-DPAT from 5-hydroxytryptamine 1A receptor in pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 25.1nMAssay Description:Binding activity against 5-hydroxytryptamine 1A receptor from pig cortex membrane using [3H]8-OH-DPAT-HT as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 500nMAssay Description:Compound was tested for its ability to displace [3H]mesulergine from 5-hydroxytryptamine 2C receptor in pig cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 501nMAssay Description:Binding activity against 5-hydroxytryptamine 2C receptor from pig cortex membrane using [3H]mesulergine as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]DOB from 5-hydroxytryptamine 2A receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding activity against 5-hydroxytryptamine 2C receptor from pig cortex membrane using [3H]mesulergine as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 1.00E+4nMAssay Description:Compound was tested for its ability to displace [3H]-Q-ICS 205-930 from 5-hydroxytryptamine 3 receptor in rat cortex homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2018
Entry Details

LigandPNGBDBM50407356(CHEMBL54265)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]-Q-ICS 205-930 binding to rat cortex homogenate 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed