BDBM50411028 CHEMBL377844

SMILES Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3CCCc4cc(F)ccc34)C(F)(F)F)cc12

InChI Key InChIKey=IFVFBECHNMWWHJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50411028   

TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411028(CHEMBL377844)
Affinity DataIC50: 13nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411028(CHEMBL377844)
Affinity DataIC50: 1.00E+3nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed