BDBM50411704 CHEMBL269959

SMILES Cc1nc2cc3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3cc2o1

InChI Key InChIKey=XQYFTHHWGHOOSS-UHFFFAOYSA-N

Data  5 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50411704   

TargetD(3) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataKi:  63.1nMAssay Description:Antagonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataKi:  63.1nMAssay Description:Antagonist activity at human dopamine D3 receptor by cell based GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataKi: >2.00E+3nMAssay Description:Antagonist activity at histamine H1 receptor by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataKi: >2.51E+3nMAssay Description:Antagonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataKi: >2.51E+3nMAssay Description:Antagonist activity at dopamine D2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]Dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50411704(CHEMBL269959)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]dofetidile from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed