BDBM50411867 CHEMBL256883

SMILES CCOc1ccccc1CNc1ncnn1-c1cccc(Cl)c1Cl

InChI Key InChIKey=PNEILCJIFNKVOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50411867   

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50411867(CHEMBL256883)
Affinity DataIC50: 45.7nMAssay Description:Antagonist activity at human recombinant P2X7 receptor assessed as inhibition of BzATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50411867(CHEMBL256883)
Affinity DataIC50: 490nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor assessed as inhibition of BzATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed