BDBM50412155 CHEMBL496299

SMILES c1ccc(c(c1)NNC(=O)C23CC4CC(C2)CC(C4)C3)Cl

InChI Key InChIKey=MRUZONZFWMDWAL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50412155   

TargetP2X purinoceptor 7(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412155BDBM50412155(CHEMBL496299)
Affinity DataIC50: 11.5nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetP2X purinoceptor 7(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50412155BDBM50412155(CHEMBL496299)
Affinity DataIC50: 33.9nMAssay Description:Antagonist activity at rat recombinant P2X7 receptor expressed in human 1321N1 cells assessed as benzoyl-ATP-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed