BDBM50412861 CHEMBL185088

SMILES CC1(C)OC[C@H](NC(=O)Nc2ccc(Br)cc2Cl)[C@@H](O1)c1ccccc1

InChI Key InChIKey=HHNAHVCOGFTMSQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50412861   

TargetOrexin receptor type 2(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50412861(CHEMBL185088)
Affinity DataKi:  6.30nMAssay Description:Binding affinity towards human orexin receptor type 2 was determined using [125I]-Orexin A as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50412861(CHEMBL185088)
Affinity DataKi:  6.31nMAssay Description:Binding affinity to OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50412861(CHEMBL185088)
Affinity DataKi: >5.01E+3nMAssay Description:Binding affinity to OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50412861(CHEMBL185088)
Affinity DataKi: <5.01E+3nMAssay Description:Binding affinity towards human orexin receptor type 1 was determined using [125I]-Orexin A as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed