BDBM50413782 CHEMBL1627325

SMILES CSCC[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(C)(C)C)C(C)C)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)O)[C@@H](C)O

InChI Key InChIKey=ABPYEHGNPGKEJG-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50413782   

TargetB2 bradykinin receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  0.0339nMAssay Description:Antagonist activity at human recombinant bradykinin 2 receptor expressed in CHO cells assessed as inhibition of bradykinin-induced intracellular calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  0.0490nMAssay Description:Antagonist activity at human recombinant NK1 receptor expressed in CHO cells assessed as inhibition of NPS-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  0.282nMAssay Description:Antagonist activity at human recombinant NOP receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of N/OFQ-induced intracellu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  1.90nMAssay Description:Antagonist activity at human recombinant delta opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of DPDPE-induced i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  2.30nMAssay Description:Antagonist activity at human recombinant kappa opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dynorphin A-ind...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  3.5nMAssay Description:Antagonist activity at human recombinant urotensin 2 receptor expressed in CHO cells assessed as inhibition of urotensin 2-induced intracellular calc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  11nMAssay Description:Antagonist activity at human recombinant mu opioid receptor expressed in CHO cells coexpressing alphaqi5 assessed as inhibition of dermorphin-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetProteinase-activated receptor 2(Human)
National Institute of Neuroscienc

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413782BDBM50413782(CHEMBL1627325)
Affinity DataEC50:  3.16E+4nMAssay Description:Antagonist activity at human recombinant PAR2 expressed in A549 cells assessed as inhibition of SLIGKV-NH2-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed