BDBM50414569 CHEMBL272511

SMILES Cc1nc2c3CCN(CCCSc4nnc(-c5cccc6nc(C)ccc56)n4C)CCc3ccc2o1

InChI Key InChIKey=HTADTAUIMFMPFI-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50414569   

TargetD(3) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataKi:  63.1nMAssay Description:Antagonist activity at human D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataKi:  63.1nMAssay Description:Binding affinity to human DRD3 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataKi: >631nMAssay Description:Antagonist activity at human D2 receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Cancer Therapeutics

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataKi: >631nMAssay Description:Binding affinity to human DRD2 receptor by GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of [3H]dofetilide from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataIC50: 2.51E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG channel by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Imperial College

Curated by ChEMBL
LigandPNGBDBM50414569(CHEMBL272511)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed