BDBM50414951 CHEMBL578805::US11753371, Compound II-2h

SMILES CCN(Cc1ccccc1)C(=S)SSC(=S)N(CC)Cc1ccccc1

InChI Key InChIKey=LHVXHXIGDKZIBU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50414951   

TargetMonoglyceride lipase(Human)
Universite Catholique De Louvain

Curated by ChEMBL
LigandPNGBDBM50414951(CHEMBL578805 | US11753371, Compound II-2h)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of human MGL activity using [3H]2-oleoylglycerol substrate by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Human)
Universite Catholique De Louvain

Curated by ChEMBL
LigandPNGBDBM50414951(CHEMBL578805 | US11753371, Compound II-2h)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human recombinant FAAH-maltose binding proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Human)
Universite Catholique De Louvain

Curated by ChEMBL
LigandPNGBDBM50414951(CHEMBL578805 | US11753371, Compound II-2h)
Affinity DataIC50:  5.53E+3nMAssay Description:The compounds II-2a to II-2m and controls in Table II were tested in 10-dose IC50 mode, with 3-fold serial dilution at a starting concentration of 10...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAldehyde dehydrogenase 1A1(Human)
Batterjee Medical College

US Patent
LigandPNGBDBM50414951(CHEMBL578805 | US11753371, Compound II-2h)
Affinity DataIC50:  270nMAssay Description:5 μl of enzyme (150 nM for ALDH1a1 and 200 nM for ALDH2 in reaction buffer) were delivered to assay wells in coming black, 384 well plate. 5 ...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetAldehyde dehydrogenase 1A1(Human)
Batterjee Medical College

US Patent
LigandPNGBDBM50414951(CHEMBL578805 | US11753371, Compound II-2h)
Affinity DataIC50:  270nMAssay Description:Inhibition of ALDH1A1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed