BDBM50415696 CHEMBL2021328

SMILES C[C@@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=AHUJWMNUJZYLEX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50415696   

TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50415696(CHEMBL2021328)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of prolyl oligopeptidase in human LNZ308 cell extracts assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50415696(CHEMBL2021328)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of prolyl oligopeptidase in human LN229 cell extracts assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50415696(CHEMBL2021328)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of prolyl oligopeptidase in human HCEC cell extracts assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50415696(CHEMBL2021328)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of prolyl oligopeptidase in intact human LNZ308 cells assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50415696(CHEMBL2021328)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of prolyl oligopeptidase in intact human HCEC cells assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50415696(CHEMBL2021328)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of prolyl oligopeptidase in intact human LN229 cells assessed as blockade of Z-Gly-Pro-AMC substrate hydrolysis by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed