BDBM50417277 CHEMBL1269249

SMILES CN1[C@@H](CNC1=O)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key InChIKey=VIXOZHAIHKRRKM-JTQLQIEISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50417277   

TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50417277(CHEMBL1269249)
Affinity DataIC50:  10nMAssay Description:Inhibition of human P2X7 expressed in human HEK293 cells assessed as reduction in BzATP-stimulated TO-PRO-3 incorporation preincubated with compound ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50417277(CHEMBL1269249)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human recombinant P2X7 receptor expressed in HEK293 cells by ethidium accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed