BDBM50418245 CHEMBL1765734
SMILES Nc1n[nH]c2cc(ccc12)-c1cc(nc(N)n1)N1CCC[C@@H](C1)C(=O)NC1CCCCC1
InChI Key InChIKey=PKLONJIIVGGTJL-HNNXBMFYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50418245
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of PDK1-mediated AKT phosphorylation at Thr308 residue in human PC3 cells by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of aurora BMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of aurora AMore data for this Ligand-Target Pair