BDBM50418849 CHEMBL1738840

SMILES COc1ccnc(CCc2nc3ncccc3[nH]2)c1

InChI Key InChIKey=YBOCDKFRGBOOFO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50418849   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50:  81.3nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50:  3.16E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50:  1.38E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418849(CHEMBL1738840)
Affinity DataIC50:  1.12E+5nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed