BDBM50418851 CHEMBL1800528

SMILES COc1ccnc(CCc2nc3nccc(C)c3[nH]2)c1

InChI Key InChIKey=UFFMLXIMOZMLNJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418851   

TargetNitric oxide synthase, inducible(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418851(CHEMBL1800528)
Affinity DataIC50: 145nMAssay Description:Inhibition of human iNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418851(CHEMBL1800528)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of human nNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50418851(CHEMBL1800528)
Affinity DataIC50: 4.57E+4nMAssay Description:Inhibition of human eNOS assessed as inhibition of [3H]L-arginine to [3H]L-citrulline conversion by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed