BDBM50418988 CHEMBL1809111

SMILES Cn1cc(-c2ccc(cc2)N2CCOCC2)c2sc(cc2c1=O)-c1ccncc1

InChI Key InChIKey=WVLBSRCGDXMGGV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50418988   

TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418988(CHEMBL1809111)
Affinity DataIC50: 251nMAssay Description:Inhibition of human full length His-tagged GSK3-beta expressed in baculovirus by alphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418988(CHEMBL1809111)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of recombinant CDK2 expressed in baculovirus using [gamma-32P]-ATP by 33-P leadseeker assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50418988(CHEMBL1809111)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human flag-tagged GSK3-beta expressed in HEK-MSRII cells assessed as CRMP-2 phosphorylation by alphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed