BDBM50419859 CHEMBL1957482
SMILES NC1=NC(C2=NCC(F)(F)CN12)(c1ccc(OC(F)F)cc1)c1cccc(OCCCF)c1
InChI Key InChIKey=CGCZYUBHKQMTSE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50419859
Affinity DataIC50: 59nMAssay Description:Inhibition of human BACE-1 using (Eu)CEVNLDAEFK(Qsy7) as substrate preincubated for 10 mins prior substrate addition measured after 15 mins by FRET-b...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE-1-mediated sAPPbeta production in human SH-SY5Y cells after 16 hrsMore data for this Ligand-Target Pair