BDBM50419872 CHEMBL1957469

SMILES COc1ccc(cc1)C1(N=C(N)N2CCCN=C12)c1cccc(c1)-c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=DTEDGQCAFBVFLT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50419872   

TargetBeta-secretase 1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50419872(CHEMBL1957469)
Affinity DataIC50:  22nMAssay Description:Inhibition of human BACE-1 using (Eu)CEVNLDAEFK(Qsy7) as substrate preincubated for 10 mins prior substrate addition measured after 15 mins by FRET-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed