BDBM50420307 CHEMBL2089062

SMILES CN(C)C1CCN(CC1)c1ccc2nc([nH]c2c1)C(=O)c1ccnc(c1)-c1cccnc1

InChI Key InChIKey=HZMPMQTVDNMJCS-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50420307   

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
TBA

Curated by ChEMBL

LigandBDBM50420307(CHEMBL2089062)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human CDK6/cyclin D3 assessed as inhibition of pRb Ser780 phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/22/2013
Entry Details Article
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TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50420307(CHEMBL2089062)Copy SMILESCopy InChI

Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of human CDK1/cyclin B assessed as inhibition of Tamra-H1 phosphorylation by IMAP-FP assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/22/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL